Strontium in PDB 1qrk: Human Factor XIII with Strontium Bound in the Ion Site

All present enzymatic activity of Human Factor XIII with Strontium Bound in the Ion Site:
2.3.2.13;

The structure of Human Factor XIII with Strontium Bound in the Ion Site, PDB code: 1qrk was solved by B.A.Fox, V.C.Yee, L.C.Pederson, I.Le Trong, P.D.Bishop, R.E.Stenkamp, D.C.Teller, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 2.50
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	101.900, 72.320, 135.030, 90.00, 105.90, 90.00
R / Rfree (%)	18.3 / 27.5

The binding sites of Strontium atom in the Human Factor XIII with Strontium Bound in the Ion Site (pdb code 1qrk). This binding sites where shown within 5.0 Angstroms radius around Strontium atom.
In total 2 binding sites of Strontium where determined in the Human Factor XIII with Strontium Bound in the Ion Site, PDB code: 1qrk:
Jump to Strontium binding site number: 1; 2;

Strontium binding site 1 out of 2 in the Human Factor XIII with Strontium Bound in the Ion Site


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 1 of Human Factor XIII with Strontium Bound in the Ion Site within 5.0Å range: probe atom residue distance (Å) B Occ A:Sr732 b:51.9 occ:1.00 O A:ALA457 2.5 35.8 1.0 OE2 A:GLU485 3.6 71.4 1.0 C A:ALA457 3.7 30.7 1.0 O A:ASN436 3.9 21.4 1.0 CD A:GLU485 4.1 69.1 1.0 OE1 A:GLU485 4.3 71.6 1.0 NZ A:LYS482 4.4 28.5 1.0 OD1 A:ASP438 4.4 28.6 1.0 CA A:ALA457 4.4 30.6 1.0 O A:SER437 4.4 21.8 1.0 CB A:ALA457 4.5 29.8 1.0 O A:HOH2077 4.6 52.5 1.0 OE2 A:GLU490 4.6 68.6 1.0 N A:THR458 4.7 30.5 1.0 C A:ASN436 4.7 20.3 1.0 CA A:THR458 4.8 29.8 1.0 O A:ILE460 4.9 23.3 1.0 CG A:GLU485 4.9 62.9 1.0 CA A:ASN436 4.9 18.5 1.0

Strontium binding site 2 out of 2 in the Human Factor XIII with Strontium Bound in the Ion Site


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 2 of Human Factor XIII with Strontium Bound in the Ion Site within 5.0Å range: probe atom residue distance (Å) B Occ B:Sr732 b:45.0 occ:1.00 O B:ALA457 2.7 28.3 1.0 OE1 B:GLU485 2.9 74.3 1.0 OD1 B:ASN436 3.4 41.8 1.0 CD B:GLU485 3.8 71.2 1.0 C B:ALA457 3.9 25.1 1.0 OE2 B:GLU485 3.9 73.5 1.0 OD1 B:ASP438 4.4 32.0 1.0 O B:ILE460 4.5 22.0 1.0 CA B:THR458 4.6 26.5 1.0 CG B:ASN436 4.6 35.1 1.0 NZ B:LYS482 4.7 26.4 1.0 OE1 B:GLU490 4.7 47.5 1.0 N B:THR458 4.7 24.4 1.0 CA B:ALA457 4.8 25.3 1.0 CB B:ALA457 4.9 24.0 1.0 O B:HOH1009 4.9 45.6 1.0 CA B:ASN436 4.9 26.3 1.0 CE B:LYS482 5.0 16.2 1.0 C B:ASN436 5.0 25.6 1.0

B.A.Fox, V.C.Yee, L.C.Pedersen, I.Le Trong, P.D.Bishop, R.E.Stenkamp, D.C.Teller. Identification of the Calcium Binding Site and A Novel Ytterbium Site in Blood Coagulation Factor XIII By X-Ray Crystallography. J.Biol.Chem. V. 274 4917 1999.
ISSN: ISSN 0021-9258
PubMed: 9988734
DOI: 10.1074/JBC.274.8.4917