Strontium in PDB 1sfc: Neuronal Synaptic Fusion Complex

The structure of Neuronal Synaptic Fusion Complex, PDB code: 1sfc was solved by R.B.Sutton, A.T.Brunger, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.40
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	98.715, 111.071, 198.844, 90.00, 90.00, 90.00
R / Rfree (%)	26.5 / 30.3

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 13;

Binding sites:

The binding sites of Strontium atom in the Neuronal Synaptic Fusion Complex (pdb code 1sfc). This binding sites where shown within 5.0 Angstroms radius around Strontium atom.
In total 13 binding sites of Strontium where determined in the Neuronal Synaptic Fusion Complex, PDB code: 1sfc:
Jump to Strontium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Strontium binding site 1 out of 13 in the Neuronal Synaptic Fusion Complex


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 1 of Neuronal Synaptic Fusion Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Sr289 b:30.8 occ:1.00 O A:HOH513 2.3 20.2 1.0 O I:HOH510 2.3 20.2 1.0 OD1 A:ASP68 2.4 32.8 1.0 OG1 I:THR79 2.4 28.6 1.0 O I:SER75 2.5 28.0 1.0 O I:HOH506 2.5 36.6 1.0 OE1 I:GLU78 2.5 31.0 1.0 OG I:SER75 2.6 28.4 1.0 CG A:ASP68 3.3 30.7 1.0 C I:SER75 3.4 27.6 1.0 OD2 A:ASP68 3.6 25.2 1.0 CD I:GLU78 3.7 30.4 1.0 CB I:SER75 3.8 25.7 1.0 CB I:THR79 3.8 28.5 1.0 CA I:SER75 3.9 26.8 1.0 NH2 B:ARG232 4.1 29.4 1.0 OE2 I:GLU78 4.2 29.1 1.0 N I:THR79 4.2 29.9 1.0 N I:GLN76 4.4 28.2 1.0 CA I:THR79 4.4 28.6 1.0 CA I:GLN76 4.7 30.0 1.0 O A:ASP68 4.7 33.6 1.0 CB A:ASP68 4.7 29.6 1.0 OE1 A:GLN71 4.7 35.8 1.0 CB I:GLU78 4.7 31.7 1.0 CG2 I:THR79 4.8 27.2 1.0 CG I:GLU78 4.8 32.0 1.0 OD1 B:ASN236 4.9 32.6 1.0

Strontium binding site 2 out of 13 in the Neuronal Synaptic Fusion Complex


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 2 of Neuronal Synaptic Fusion Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Sr290 b:50.5 occ:1.00 O A:SER75 2.4 37.1 1.0 O A:HOH507 2.5 30.3 1.0 OG1 A:THR79 2.7 33.9 1.0 OD1 I:ASP68 2.7 30.1 1.0 OG A:SER75 2.8 31.6 1.0 OE1 A:GLU78 3.0 29.6 1.0 C5 I:MPD930 3.2 66.0 1.0 C A:SER75 3.2 35.1 1.0 CG I:ASP68 3.6 28.3 1.0 OD2 I:ASP68 3.8 26.3 1.0 CA A:SER75 3.8 33.1 1.0 CB A:SER75 3.8 32.5 1.0 C4 I:MPD930 3.8 68.4 1.0 CB A:THR79 4.0 31.2 1.0 N A:GLN76 4.2 36.7 1.0 CD A:GLU78 4.2 30.9 1.0 N A:THR79 4.3 31.8 1.0 NH2 J:ARG232 4.3 31.9 1.0 CA A:GLN76 4.6 36.8 1.0 CA A:THR79 4.6 31.1 1.0 CB A:GLU78 4.6 29.4 1.0 C3 I:MPD930 4.7 69.6 1.0 O I:HOH502 4.7 16.4 1.0 NE2 I:GLN71 4.8 37.9 1.0 OE1 I:GLN71 4.9 37.6 1.0 ND2 J:ASN236 5.0 33.1 1.0 CG A:GLU78 5.0 30.7 1.0

Strontium binding site 3 out of 13 in the Neuronal Synaptic Fusion Complex


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 3 of Neuronal Synaptic Fusion Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Sr294 b:96.1 occ:0.89 OD2 B:ASP218 3.4 43.0 1.0 OD1 B:ASP218 3.5 41.7 1.0 CG B:ASP218 3.9 40.6 1.0 CB B:ASP214 4.5 45.4 1.0 OD2 B:ASP214 4.9 56.7 1.0

Strontium binding site 4 out of 13 in the Neuronal Synaptic Fusion Complex


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 4 of Neuronal Synaptic Fusion Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Sr295 b:87.8 occ:0.53 O C:HOH519 3.0 40.7 1.0 SR C:SR296 3.7 96.1 0.7

Strontium binding site 5 out of 13 in the Neuronal Synaptic Fusion Complex


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 5 of Neuronal Synaptic Fusion Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Sr296 b:96.1 occ:0.67 O C:HOH519 3.0 40.7 1.0 SR C:SR295 3.7 87.8 0.5 OE2 C:GLU37 4.4 54.5 1.0

Strontium binding site 6 out of 13 in the Neuronal Synaptic Fusion Complex


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 6 of Neuronal Synaptic Fusion Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Sr288 b:58.5 occ:1.00 O D:HOH516 2.4 40.1 1.0 OE2 D:GLU170 3.9 39.8 1.0 OD2 C:ASP58 4.5 38.6 1.0 OD1 C:ASP58 4.6 38.5 1.0 OE1 D:GLU170 4.6 40.8 1.0 OE1 D:GLN177 4.7 27.8 1.0 CD D:GLU170 4.7 39.3 1.0 CG2 D:THR173 4.8 39.4 1.0 CG C:ASP58 5.0 38.6 1.0 CG D:GLN174 5.0 26.4 1.0

Strontium binding site 7 out of 13 in the Neuronal Synaptic Fusion Complex


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 7 of Neuronal Synaptic Fusion Complex within 5.0Å range: probe atom residue distance (Å) B Occ F:Sr291 b:63.7 occ:1.00 OD1 J:ASP242 2.6 35.9 1.0 O F:HOH504 2.6 27.8 1.0 OE1 F:GLU245 2.6 41.1 1.0 O J:HOH508 2.6 43.4 1.0 OD1 F:ASP242 2.7 32.6 1.0 OE2 J:GLU245 2.8 36.6 1.0 O F:HOH511 3.1 29.4 1.0 O F:HOH509 3.1 41.7 1.0 O F:HOH512 3.2 33.2 1.0 CD F:GLU245 3.4 39.0 1.0 CG J:ASP242 3.6 32.8 1.0 CD J:GLU245 3.6 36.0 1.0 OE2 F:GLU245 3.7 41.4 1.0 OE1 J:GLU245 3.9 40.7 1.0 CG F:ASP242 3.9 31.5 1.0 NH2 J:ARG246 4.0 65.7 1.0 OD2 J:ASP242 4.2 34.9 1.0 CA J:ASP242 4.4 27.6 1.0 CA F:ASP242 4.5 29.5 1.0 CB J:ASP242 4.5 31.0 1.0 CB F:ASP242 4.7 32.5 1.0 CG F:GLU245 4.7 36.5 1.0 OD2 F:ASP242 4.8 35.7 1.0 CG J:GLU245 4.8 34.5 1.0 CZ J:ARG246 5.0 65.9 1.0

Strontium binding site 8 out of 13 in the Neuronal Synaptic Fusion Complex


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 8 of Neuronal Synaptic Fusion Complex within 5.0Å range: probe atom residue distance (Å) B Occ F:Sr297 b:95.4 occ:1.00 O F:HOH501 2.6 25.2 1.0 OD1 F:ASP218 2.8 45.2 1.0 OD2 F:ASP214 2.8 49.5 1.0 OD1 F:ASP214 3.0 50.9 1.0 OD2 F:ASP218 3.1 49.2 1.0 CG F:ASP214 3.3 49.8 1.0 CG F:ASP218 3.3 46.8 1.0 O F:ASP214 4.7 43.7 1.0 CB F:ASP214 4.8 46.6 1.0 CB F:ASP218 4.8 42.9 1.0

Strontium binding site 9 out of 13 in the Neuronal Synaptic Fusion Complex


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 9 of Neuronal Synaptic Fusion Complex within 5.0Å range: probe atom residue distance (Å) B Occ G:Sr298 b:63.9 occ:1.00 OE2 G:GLU55 2.4 44.2 1.0 OD2 G:ASP51 2.8 41.2 1.0 SR G:SR299 3.3 92.6 1.0 CD G:GLU55 3.5 42.0 1.0 SR G:SR300 3.6 81.9 1.0 CG G:ASP51 3.7 39.3 1.0 OD1 G:ASP51 3.9 41.9 1.0 CG G:GLU55 4.1 37.1 1.0 OE1 G:GLU55 4.6 43.7 1.0

Strontium binding site 10 out of 13 in the Neuronal Synaptic Fusion Complex


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 10 of Neuronal Synaptic Fusion Complex within 5.0Å range: probe atom residue distance (Å) B Occ G:Sr299 b:92.6 occ:1.00 SR G:SR298 3.3 63.9 1.0 OD1 G:ASP51 3.6 41.9 1.0 OD2 G:ASP51 4.4 41.2 1.0 CG G:ASP51 4.5 39.3 1.0 OE2 G:GLU55 4.8 44.2 1.0

R.B.Sutton, D.Fasshauer, R.Jahn, A.T.Brunger. Crystal Structure of A Snare Complex Involved in Synaptic Exocytosis at 2.4 A Resolution. Nature V. 395 347 1998.
ISSN: ISSN 0028-0836
PubMed: 9759724
DOI: 10.1038/26412