Strontium in the structure of Base-Tetrad Swapping Results in Dimerization Of Rna Quadruplexes: Implications For Formation of I-Motif Rna Octaplex (pdb 2awe)

The binding sites of Strontium atom in the structure of Base-Tetrad Swapping Results in Dimerization Of Rna Quadruplexes: Implications For Formation of I-Motif Rna Octaplex (pdb code 2awe). This binding sites where shown with 5.0 Angstroms radius around Strontium atom. The 2awe structure was solved by B.PAN, K.SHI, M.SUNDARALINGAM, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 19.4-2.1 Space group I41221 a (A) 82.667 b (A) 82.667 c (A) 74.154 alpha (°) 90.00 beta (°) 90.00 gamma (°) 90.00 Rfactor (%) 17.2 Rfree (%) 22.8 Strontium Binding Sites: Strontium binding site 1 out of 1 in 2awe Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Strontium in the PDB 2awe. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Strontium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: G3, A: U4, A: G5, A: U6, C: G5, A: Hoh223, A: Hoh225, C: Hoh222, C: Hoh237, conact list: Atom Atom Distance (A) Sr C3' A:G3 4.63 Sr O3' A:G3 4.35 Sr C2' A:G3 4.29 Sr O2' A:G3 3.28 Sr OP1 A:U4 4.94 Sr P A:U4 3.98 Sr OP2 A:U4 2.61 Sr O5' A:U4 4.91 Sr OP1 A:G5 4.45 Sr C3' A:U6 3.80 Sr C1' A:U6 4.20 Sr O2 A:U6 4.75 Sr O3' A:U6 2.76 Sr C2' A:U6 3.72 Sr C4' A:U6 4.90 Sr O2' A:U6 2.83 Sr O2' C:G5 4.64 Sr O A:Hoh223 2.82 Sr O A:Hoh225 2.85 Sr O C:Hoh222 2.64 Sr O C:Hoh237 2.52 interactive model: