Strontium in PDB 2box: Egf Domains 1,2,5 of Human EMR2, A 7-Tm Immune System Molecule, in Complex with Strontium.

The structure of Egf Domains 1,2,5 of Human EMR2, A 7-Tm Immune System Molecule, in Complex with Strontium., PDB code: 2box was solved by R.J.M.Abbott, I.Spendlove, P.Roversi, P.Teriete, V.Knott, P.A.Handford, J.M.Mcdonnell, S.M.Lea, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	23.262 / 2.50
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	91.106, 61.575, 35.495, 90.00, 90.00, 90.00
R / Rfree (%)	24.03 / 28.44

The structure of Egf Domains 1,2,5 of Human EMR2, A 7-Tm Immune System Molecule, in Complex with Strontium. also contains other interesting chemical elements:

Arsenic	(As)	1 atom
Chlorine	(Cl)	1 atom

The binding sites of Strontium atom in the Egf Domains 1,2,5 of Human EMR2, A 7-Tm Immune System Molecule, in Complex with Strontium. (pdb code 2box). This binding sites where shown within 5.0 Angstroms radius around Strontium atom.
In total 2 binding sites of Strontium where determined in the Egf Domains 1,2,5 of Human EMR2, A 7-Tm Immune System Molecule, in Complex with Strontium., PDB code: 2box:
Jump to Strontium binding site number: 1; 2;

Strontium binding site 1 out of 2 in the Egf Domains 1,2,5 of Human EMR2, A 7-Tm Immune System Molecule, in Complex with Strontium.


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 1 of Egf Domains 1,2,5 of Human EMR2, A 7-Tm Immune System Molecule, in Complex with Strontium. within 5.0Å range: probe atom residue distance (Å) B Occ A:Sr1144 b:25.4 occ:1.00 OE2 A:GLU98 2.4 23.6 1.0 O A:VAL96 2.5 22.6 1.0 O A:SER118 2.6 30.0 1.0 OD1 A:ASP95 2.6 30.1 1.0 O A:THR115 2.6 31.9 1.0 OD1 A:ASN114 2.7 28.2 1.0 O A:HOH2076 2.7 13.8 1.0 OD2 A:ASP95 3.0 35.9 1.0 CG A:ASP95 3.2 29.4 1.0 CD A:GLU98 3.4 37.5 1.0 C A:SER118 3.6 30.7 1.0 C A:VAL96 3.6 23.4 1.0 N A:SER118 3.6 27.6 1.0 CG A:ASN114 3.7 37.9 1.0 OE1 A:GLU98 3.7 26.0 1.0 C A:THR115 3.9 32.6 1.0 N A:GLY117 4.0 27.6 1.0 CA A:SER118 4.0 27.3 1.0 ND2 A:ASN114 4.0 25.9 1.0 N A:THR115 4.2 30.0 1.0 N A:VAL96 4.3 19.9 1.0 C A:GLY117 4.3 30.8 1.0 N A:GLU98 4.4 24.0 1.0 CA A:ASP97 4.4 21.0 1.0 N A:ASP97 4.4 20.8 1.0 CA A:VAL96 4.5 19.7 1.0 O A:GLY75 4.6 24.5 1.0 CA A:GLY117 4.6 27.2 1.0 CB A:ASP95 4.7 19.9 1.0 N A:TYR119 4.7 27.1 1.0 CG A:GLU98 4.7 30.5 1.0 CA A:VAL116 4.7 28.8 1.0 CA A:THR115 4.7 29.5 1.0 C A:VAL116 4.8 31.9 1.0 N A:VAL116 4.8 29.1 1.0 CB A:TYR119 4.9 27.4 1.0 CB A:ASN114 5.0 29.0 1.0 C A:ASP97 5.0 26.3 1.0 C A:ASP95 5.0 22.8 1.0 CB A:VAL96 5.0 23.5 1.0 OG1 A:THR115 5.0 37.0 1.0

Strontium binding site 2 out of 2 in the Egf Domains 1,2,5 of Human EMR2, A 7-Tm Immune System Molecule, in Complex with Strontium.


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 2 of Egf Domains 1,2,5 of Human EMR2, A 7-Tm Immune System Molecule, in Complex with Strontium. within 5.0Å range: probe atom residue distance (Å) B Occ A:Sr1145 b:23.0 occ:1.00 O A:ILE44 2.5 19.4 1.0 OD1 A:ASN63 2.5 20.0 1.0 O A:SER67 2.5 23.3 1.0 O A:THR64 2.6 20.3 1.0 CL A:CL1146 2.6 19.9 1.0 OE1 A:GLU46 2.6 26.5 1.0 OD1 A:ASP43 2.7 24.2 1.0 OD2 A:ASP43 2.9 30.6 1.0 CG A:ASP43 3.1 24.5 1.0 C A:SER67 3.6 23.5 1.0 N A:SER67 3.6 21.7 1.0 CG A:ASN63 3.6 26.2 1.0 CD A:GLU46 3.6 30.1 1.0 C A:ILE44 3.6 19.9 1.0 C A:THR64 3.8 21.1 1.0 OE2 A:GLU46 3.8 17.8 1.0 N A:GLY66 4.0 20.9 1.0 CA A:SER67 4.0 20.7 1.0 ND2 A:ASN63 4.1 16.2 1.0 N A:THR64 4.1 15.2 1.0 N A:ILE44 4.2 17.1 1.0 C A:GLY66 4.2 25.3 1.0 CA A:ASN45 4.4 16.7 1.0 N A:GLU46 4.4 19.3 1.0 N A:ASN45 4.4 16.8 1.0 CA A:ILE44 4.5 16.7 1.0 CA A:GLY66 4.6 20.7 1.0 O A:GLY26 4.6 19.1 1.0 CB A:ASP43 4.6 18.0 1.0 CA A:THR64 4.6 15.5 1.0 N A:TYR68 4.7 18.8 1.0 C A:GLU65 4.7 24.3 1.0 N A:GLU65 4.8 19.3 1.0 CA A:GLU65 4.8 19.5 1.0 CB A:ASN63 4.8 11.6 1.0 C A:ASP43 4.9 20.3 1.0 CG A:GLU46 4.9 24.8 1.0 C A:ASN63 5.0 18.1 1.0 C A:ASN45 5.0 21.7 1.0

R.J.M.Abbott, I.Spendlove, P.Roversi, H.Fitzgibbon, V.Knott, P.Teriete, J.M.Mcdonnell, P.A.Handford, S.M.Lea. Structural and Functional Characterization of A Novel T Cell Receptor Co-Regulatory Protein Complex, CD97-CD55. J.Biol.Chem. V. 282 22023 2007.
ISSN: ISSN 0021-9258
PubMed: 17449467
DOI: 10.1074/JBC.M702588200