Strontium in PDB 3p4c: Alternatingly Modified 2'Fluoro Rna Octamer F/RA2U2-R32

The structure of Alternatingly Modified 2'Fluoro Rna Octamer F/RA2U2-R32, PDB code: 3p4c was solved by P.S.Pallan, E.M.Greene, P.A.Jicman, R.K.Pandey, M.Manoharan, E.Rozners, M.Egli, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.15
Space group	H 3 2
Cell size a, b, c (Å), α, β, γ (°)	40.550, 40.550, 117.222, 90.00, 90.00, 120.00
R / Rfree (%)	18.2 / 24.9

The structure of Alternatingly Modified 2'Fluoro Rna Octamer F/RA2U2-R32 also contains other interesting chemical elements:

Fluorine

(F)

8 atoms

The binding sites of Strontium atom in the Alternatingly Modified 2'Fluoro Rna Octamer F/RA2U2-R32 (pdb code 3p4c). This binding sites where shown within 5.0 Angstroms radius around Strontium atom.
In total 3 binding sites of Strontium where determined in the Alternatingly Modified 2'Fluoro Rna Octamer F/RA2U2-R32, PDB code: 3p4c:
Jump to Strontium binding site number: 1; 2; 3;

Strontium binding site 1 out of 3 in the Alternatingly Modified 2'Fluoro Rna Octamer F/RA2U2-R32


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 1 of Alternatingly Modified 2'Fluoro Rna Octamer F/RA2U2-R32 within 5.0Å range: probe atom residue distance (Å) B Occ B:Sr301 b:19.5 occ:1.00 O5' B:CFZ209 2.2 17.7 0.8 OP2 B:G210 2.5 20.0 1.0 C5' B:CFZ209 3.4 20.8 0.8 O B:HOH323 3.4 38.7 1.0 P B:G210 3.8 16.4 1.0 C3' B:CFZ209 4.0 16.0 0.8 O3' B:CFZ209 4.2 20.6 0.8 C4' B:CFZ209 4.3 17.1 0.8 OP1 B:G210 4.6 26.0 1.0 O A:HOH327 4.8 27.1 1.0 O5' B:G210 4.9 18.9 1.0

Strontium binding site 2 out of 3 in the Alternatingly Modified 2'Fluoro Rna Octamer F/RA2U2-R32


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 2 of Alternatingly Modified 2'Fluoro Rna Octamer F/RA2U2-R32 within 5.0Å range: probe atom residue distance (Å) B Occ B:Sr302 b:27.1 occ:1.00 O A:HOH355 1.8 17.5 0.7 O B:HOH375 2.4 25.2 1.0 O B:HOH336 2.4 26.2 1.0 O A:HOH334 2.4 21.6 1.0 O A:HOH310 2.5 23.4 1.0 O4 B:UFT213 2.7 15.7 1.0 O B:HOH352 2.8 31.3 1.0 O A:HOH372 2.8 41.8 1.0 O B:HOH308 2.9 15.1 0.5 O A:HOH337 3.5 23.8 1.0 C4 B:UFT213 3.7 14.2 1.0 C5 B:UFT213 4.3 14.0 1.0 O B:HOH388 4.3 28.9 1.0 O B:HOH384 4.4 54.3 1.0 O A:HOH380 4.5 49.4 1.0 N6 A:A104 4.5 13.3 1.0 O4 B:U214 4.6 10.8 1.0 O B:HOH373 4.6 22.8 1.0 N7 B:A212 4.6 11.7 1.0 N6 B:A212 4.6 12.8 1.0 O B:HOH341 4.6 38.5 1.0 N6 A:AF2103 4.6 9.8 1.0 N3 B:UFT213 4.9 12.3 1.0

Strontium binding site 3 out of 3 in the Alternatingly Modified 2'Fluoro Rna Octamer F/RA2U2-R32


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 3 of Alternatingly Modified 2'Fluoro Rna Octamer F/RA2U2-R32 within 5.0Å range: probe atom residue distance (Å) B Occ B:Sr303 b:77.1 occ:0.33 O B:HOH378 2.1 16.7 0.6 O B:HOH390 3.8 59.7 1.0 O B:HOH342 3.8 24.0 1.0 O B:HOH386 3.9 41.2 1.0 O A:HOH338 4.3 20.7 1.0 F2' B:UFT213 4.7 12.3 1.0 O B:HOH345 4.8 16.0 1.0 O4' B:UFT213 4.8 13.4 1.0

P.S.Pallan, E.M.Greene, P.A.Jicman, R.K.Pandey, M.Manoharan, E.Rozners, M.Egli. Unexpected Origins of the Enhanced Pairing Affinity of 2'-Fluoro-Modified Rna. Nucleic Acids Res. V. 39 3482 2011.
ISSN: ISSN 0305-1048
PubMed: 21183463
DOI: 10.1093/NAR/GKQ1270