Strontium in PDB 5ew4: Crystal Structure of C9ORF72 Antisense Ccccgg Repeat Rna Associated with Lou Gehrig'S Disease and Frontotemporal Dementia, Crystallized with SR2+

The structure of Crystal Structure of C9ORF72 Antisense Ccccgg Repeat Rna Associated with Lou Gehrig'S Disease and Frontotemporal Dementia, Crystallized with SR2+, PDB code: 5ew4 was solved by D.R.Tomchick, D.W.Dodd, K.T.Gagnon, D.R.Corey, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	23.92 / 1.47
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	41.020, 47.615, 58.900, 90.00, 90.00, 90.00
R / Rfree (%)	21.6 / 23.9

The structure of Crystal Structure of C9ORF72 Antisense Ccccgg Repeat Rna Associated with Lou Gehrig'S Disease and Frontotemporal Dementia, Crystallized with SR2+ also contains other interesting chemical elements:

Magnesium	(Mg)	2 atoms
Potassium	(K)	9 atoms
Chlorine	(Cl)	1 atom

The binding sites of Strontium atom in the Crystal Structure of C9ORF72 Antisense Ccccgg Repeat Rna Associated with Lou Gehrig'S Disease and Frontotemporal Dementia, Crystallized with SR2+ (pdb code 5ew4). This binding sites where shown within 5.0 Angstroms radius around Strontium atom.
In total only one binding site of Strontium was determined in the Crystal Structure of C9ORF72 Antisense Ccccgg Repeat Rna Associated with Lou Gehrig'S Disease and Frontotemporal Dementia, Crystallized with SR2+, PDB code: 5ew4:

Strontium binding site 1 out of 1 in the Crystal Structure of C9ORF72 Antisense Ccccgg Repeat Rna Associated with Lou Gehrig'S Disease and Frontotemporal Dementia, Crystallized with SR2+


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 1 of Crystal Structure of C9ORF72 Antisense Ccccgg Repeat Rna Associated with Lou Gehrig'S Disease and Frontotemporal Dementia, Crystallized with SR2+ within 5.0Å range: probe atom residue distance (Å) B Occ B:Sr101 b:12.5 occ:1.00 O2 B:C16 2.4 12.4 1.0 O A:HOH268 2.6 17.5 1.0 O B:HOH241 2.7 15.3 1.0 O B:HOH257 2.7 12.7 1.0 C2 B:C16 3.5 9.6 1.0 H1' B:C16 4.0 15.1 1.0 N3 B:C16 4.1 10.5 1.0 H1' A:C10 4.3 13.6 1.0 H1' B:G17 4.3 11.8 1.0 H2' B:C16 4.5 14.8 1.0 N1 B:C16 4.5 11.2 1.0 C1' B:C16 4.6 12.6 1.0 O A:HOH266 4.7 32.6 1.0 O4' B:G17 4.7 10.1 1.0 O2' A:C10 4.8 13.1 1.0 O2' B:C16 4.8 14.9 1.0 O B:HOH250 4.8 16.5 1.0 C2' B:C16 4.8 12.3 1.0 C1' B:G17 4.9 9.9 1.0

D.W.Dodd, D.R.Tomchick, D.R.Corey, K.T.Gagnon. Pathogenic C9ORF72 Antisense Repeat Rna Forms A Double Helix with Tandem C:C Mismatches. Biochemistry V. 55 1283 2016.
ISSN: ISSN 0006-2960
PubMed: 26878348
DOI: 10.1021/ACS.BIOCHEM.6B00136