Strontium in PDB 6h5r: Structure of the Complex of A Human Telomeric Dna with Bis(1-Butyl-3- Methyl-Imidazole-2-Ylidene) Gold(I)

The structure of Structure of the Complex of A Human Telomeric Dna with Bis(1-Butyl-3- Methyl-Imidazole-2-Ylidene) Gold(I), PDB code: 6h5r was solved by C.Bazzicalupi, P.Gratteri, F.Papi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.69 / 2.00
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	36.600, 71.370, 27.050, 90.00, 92.42, 90.00
R / Rfree (%)	22.8 / 25.3

The structure of Structure of the Complex of A Human Telomeric Dna with Bis(1-Butyl-3- Methyl-Imidazole-2-Ylidene) Gold(I) also contains other interesting chemical elements:

Gold	(Au)	4 atoms
Potassium	(K)	2 atoms

The binding sites of Strontium atom in the Structure of the Complex of A Human Telomeric Dna with Bis(1-Butyl-3- Methyl-Imidazole-2-Ylidene) Gold(I) (pdb code 6h5r). This binding sites where shown within 5.0 Angstroms radius around Strontium atom.
In total only one binding site of Strontium was determined in the Structure of the Complex of A Human Telomeric Dna with Bis(1-Butyl-3- Methyl-Imidazole-2-Ylidene) Gold(I), PDB code: 6h5r:

Strontium binding site 1 out of 1 in the Structure of the Complex of A Human Telomeric Dna with Bis(1-Butyl-3- Methyl-Imidazole-2-Ylidene) Gold(I)


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 1 of Structure of the Complex of A Human Telomeric Dna with Bis(1-Butyl-3- Methyl-Imidazole-2-Ylidene) Gold(I) within 5.0Å range: probe atom residue distance (Å) B Occ A:Sr103 b:31.4 occ:0.50 O6 A:DG3 3.1 20.3 1.0 O6 A:DG15 3.1 19.1 1.0 O6 A:DG9 3.1 20.4 1.0 O6 A:DG21 3.1 21.1 1.0 K A:K102 3.7 19.9 1.0 C6 A:DG3 3.9 22.1 1.0 C6 A:DG21 3.9 22.6 1.0 C6 A:DG15 3.9 20.7 1.0 C6 A:DG9 3.9 21.7 1.0 N1 A:DG21 4.2 22.2 1.0 N1 A:DG3 4.2 21.7 1.0 N1 A:DG9 4.2 21.4 1.0 N1 A:DG15 4.3 20.7 1.0

F.Guarra, T.Marzo, M.Ferraroni, F.Papi, C.Bazzicalupi, P.Gratteri, G.Pescitelli, L.Messori, T.Biver, C.Gabbiani. Interaction of A Gold(I) Dicarbene Anticancer Drug with Human Telomeric Dna G-Quadruplex: Solution and Computationally Aided X-Ray Diffraction Analysis. Dalton Trans V. 47 16132 2018.
ISSN: ESSN 1477-9234
PubMed: 30378627
DOI: 10.1039/C8DT03607A