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Strontium in PDB 7oos: The Crystal Structure of A Dna:Rna Hybrid Duplex Sequence Cttttctttg

Protein crystallography data

The structure of The Crystal Structure of A Dna:Rna Hybrid Duplex Sequence Cttttctttg, PDB code: 7oos was solved by C.Thorpe, J.Hardwick, M.A.Mcdonough, J.P.Hall, Y.R.Baker, A.H.El-Sagheer, T.Brown, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.75 / 2.60
Space group P 61
Cell size a, b, c (Å), α, β, γ (°) 55.14, 55.14, 45.96, 90, 90, 120
R / Rfree (%) 21.8 / 23.4

Strontium Binding Sites:

The binding sites of Strontium atom in the The Crystal Structure of A Dna:Rna Hybrid Duplex Sequence Cttttctttg (pdb code 7oos). This binding sites where shown within 5.0 Angstroms radius around Strontium atom.
In total 2 binding sites of Strontium where determined in the The Crystal Structure of A Dna:Rna Hybrid Duplex Sequence Cttttctttg, PDB code: 7oos:
Jump to Strontium binding site number: 1; 2;

Strontium binding site 1 out of 2 in 7oos

Go back to Strontium Binding Sites List in 7oos
Strontium binding site 1 out of 2 in the The Crystal Structure of A Dna:Rna Hybrid Duplex Sequence Cttttctttg


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 1 of The Crystal Structure of A Dna:Rna Hybrid Duplex Sequence Cttttctttg within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Sr101

b:135.8
occ:1.00
O A:HOH201 3.1 73.6 1.0
N7 A:A9 4.4 68.3 1.0
N7 A:G10 4.6 70.5 1.0
N6 A:A9 4.6 64.2 1.0
O6 A:G10 4.7 72.0 1.0

Strontium binding site 2 out of 2 in 7oos

Go back to Strontium Binding Sites List in 7oos
Strontium binding site 2 out of 2 in the The Crystal Structure of A Dna:Rna Hybrid Duplex Sequence Cttttctttg


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 2 of The Crystal Structure of A Dna:Rna Hybrid Duplex Sequence Cttttctttg within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Sr102

b:123.5
occ:1.00
O A:HOH202 3.2 68.4 1.0
N7 A:G5 4.4 62.3 1.0
OP2 A:G5 4.8 90.0 1.0
N7 A:A4 4.9 63.9 1.0
N6 A:A6 4.9 55.1 1.0
O6 A:G5 4.9 62.8 1.0

Reference:

Y.R.Baker, C.Thorpe, J.Chen, L.M.Poller, L.Cox, P.Kumar, W.F.Lim, L.Lie, G.Mcclorey, S.Epple, D.Singleton, M.A.Mcdonough, J.S.Hardwick, K.E.Christensen, M.J.A.Wood, J.P.Hall, A.H.El-Sagheer, T.Brown. An Lna-Amide Modification That Enhances the Cell Uptake and Activity of Phosphorothioate Exon-Skipping Oligonucleotides. Nat Commun V. 13 4036 2022.
ISSN: ESSN 2041-1723
PubMed: 35821218
DOI: 10.1038/S41467-022-31636-2
Page generated: Fri Oct 11 07:06:07 2024

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