Strontium in PDB 7xh9: Crystal Structure of A Dimeric Interlocked Parallel G-Quadruplex

The structure of Crystal Structure of A Dimeric Interlocked Parallel G-Quadruplex, PDB code: 7xh9 was solved by K.H.Ngo, C.W.Liew, S.Lattmann, F.R.Winnerdy, A.T.Phan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.33 / 1.63
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	26.436, 30.341, 30.35, 62.15, 79.96, 79.97
R / Rfree (%)	22.5 / 24.7

The structure of Crystal Structure of A Dimeric Interlocked Parallel G-Quadruplex also contains other interesting chemical elements:

Potassium

(K)

5 atoms

The binding sites of Strontium atom in the Crystal Structure of A Dimeric Interlocked Parallel G-Quadruplex (pdb code 7xh9). This binding sites where shown within 5.0 Angstroms radius around Strontium atom.
In total 4 binding sites of Strontium where determined in the Crystal Structure of A Dimeric Interlocked Parallel G-Quadruplex, PDB code: 7xh9:
Jump to Strontium binding site number: 1; 2; 3; 4;

Strontium binding site 1 out of 4 in the Crystal Structure of A Dimeric Interlocked Parallel G-Quadruplex


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 1 of Crystal Structure of A Dimeric Interlocked Parallel G-Quadruplex within 5.0Å range: probe atom residue distance (Å) B Occ A:Sr104 b:56.2 occ:1.00 O A:HOH211 2.8 41.2 1.0 O4' B:DG7 4.6 40.8 1.0 O4' A:DG3 4.7 43.3 1.0 N2 B:DG6 4.7 36.9 1.0 C4' B:DG7 4.8 47.0 1.0 N3 A:DG2 4.8 37.0 1.0 N2 A:DG2 4.9 37.6 1.0 O A:HOH207 4.9 41.2 1.0

Strontium binding site 2 out of 4 in the Crystal Structure of A Dimeric Interlocked Parallel G-Quadruplex


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 2 of Crystal Structure of A Dimeric Interlocked Parallel G-Quadruplex within 5.0Å range: probe atom residue distance (Å) B Occ A:Sr105 b:55.0 occ:1.00 O B:HOH213 2.7 41.5 1.0 O A:HOH217 4.4 43.0 1.0 O4' A:DG7 4.7 43.9 1.0 O4' B:DG3 4.7 41.5 1.0 N2 A:DG6 4.8 38.5 1.0 N2 B:DG2 4.8 35.5 1.0 N3 B:DG2 4.8 36.4 1.0 O B:HOH203 4.9 42.3 1.0 C4' A:DG7 4.9 46.7 1.0

Strontium binding site 3 out of 4 in the Crystal Structure of A Dimeric Interlocked Parallel G-Quadruplex


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 3 of Crystal Structure of A Dimeric Interlocked Parallel G-Quadruplex within 5.0Å range: probe atom residue distance (Å) B Occ A:Sr106 b:111.9 occ:1.00 OP2 A:DT5 4.3 53.0 1.0 O3' A:DG4 4.6 46.1 1.0

Strontium binding site 4 out of 4 in the Crystal Structure of A Dimeric Interlocked Parallel G-Quadruplex


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 4 of Crystal Structure of A Dimeric Interlocked Parallel G-Quadruplex within 5.0Å range: probe atom residue distance (Å) B Occ A:Sr107 b:92.5 occ:1.00 C7 A:DT16 3.3 100.6 1.0 C5 A:DT16 4.1 99.3 1.0 C4 A:DT16 4.7 101.3 1.0 C6 A:DT16 4.7 92.5 1.0 O4 A:DT16 4.7 103.9 1.0

K.H.Ngo, C.W.Liew, S.Lattmann, F.R.Winnerdy, A.T.Phan. Crystal Structures of An Hiv-1 Integrase Aptamer: Formation of A Water-Mediated A.G.G.G.G Pentad in An Interlocked G-Quadruplex. Biochem.Biophys.Res.Commun. V. 613 153 2022.
ISSN: ESSN 1090-2104
PubMed: 35561583
DOI: 10.1016/J.BBRC.2022.04.020