Strontium in PDB 8cve: Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Iron, 2-Oxoglutarate, and Hyoscyamine

All present enzymatic activity of Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Iron, 2-Oxoglutarate, and Hyoscyamine:
1.14.11.11;

The structure of Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Iron, 2-Oxoglutarate, and Hyoscyamine, PDB code: 8cve was solved by E.W.Wenger, A.K.Boal, J.M.Bollinger, C.Krebs, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.53 / 1.53
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	44.763, 79.215, 55.757, 90, 111.05, 90
R / Rfree (%)	18.5 / 20.4

The structure of Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Iron, 2-Oxoglutarate, and Hyoscyamine also contains other interesting chemical elements:

Iron

(Fe)

1 atom

The binding sites of Strontium atom in the Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Iron, 2-Oxoglutarate, and Hyoscyamine (pdb code 8cve). This binding sites where shown within 5.0 Angstroms radius around Strontium atom.
In total 2 binding sites of Strontium where determined in the Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Iron, 2-Oxoglutarate, and Hyoscyamine, PDB code: 8cve:
Jump to Strontium binding site number: 1; 2;

Strontium binding site 1 out of 2 in the Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Iron, 2-Oxoglutarate, and Hyoscyamine


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 1 of Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Iron, 2-Oxoglutarate, and Hyoscyamine within 5.0Å range: probe atom residue distance (Å) B Occ A:Sr414 b:9.3 occ:0.95 O A:GLY98 2.5 11.7 1.0 OE1 A:GLN95 2.5 11.5 1.0 OE2 A:GLU92 2.6 11.2 1.0 O A:HOH745 2.7 14.5 1.0 OE1 A:GLU92 2.8 11.4 1.0 CD A:GLU92 3.1 11.3 1.0 C A:GLY98 3.6 11.7 1.0 CD A:GLN95 3.6 11.7 1.0 NE2 A:GLN95 4.0 12.1 1.0 CA A:GLY98 4.4 11.8 1.0 N A:GLU99 4.4 11.9 1.0 CA A:GLU99 4.5 12.4 1.0 CG A:GLU92 4.6 11.5 1.0 O A:HOH623 4.8 19.6 1.0 CG A:GLN95 4.8 11.5 1.0 CB A:GLN95 4.9 11.5 1.0 O A:HOH606 4.9 10.1 1.0

Strontium binding site 2 out of 2 in the Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Iron, 2-Oxoglutarate, and Hyoscyamine


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 2 of Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Iron, 2-Oxoglutarate, and Hyoscyamine within 5.0Å range: probe atom residue distance (Å) B Occ A:Sr415 b:19.7 occ:0.62 O A:HOH744 2.4 31.1 1.0 O A:HOH742 2.5 32.9 1.0 O A:ASN145 2.5 16.6 1.0 O A:HOH564 2.5 33.4 1.0 O A:HOH706 2.6 27.0 1.0 O A:HOH645 2.9 27.2 1.0 C A:ASN145 3.6 16.9 1.0 CA A:SER146 4.3 15.4 1.0 N A:SER146 4.4 16.0 1.0 NH2 A:ARG155 4.4 13.4 1.0 OE2 A:GLU149 4.4 20.9 1.0 CA A:ASN145 4.7 17.8 1.0 O A:HOH782 4.7 33.0 1.0 CB A:ASN145 4.8 19.1 1.0 O A:HOH507 4.8 27.5 1.0 O A:HOH787 4.9 34.5 1.0

E.S.Wenger, A.K.Boal, J.M.Bollinger, C.Krebs. Structure of the L289F H6H Hydroxylation Reactant Complex To Be Published.