Strontium in PDB 4rby: First X-Ray Structure of Rna Containing Guanosine Phosphorodithioate

The structure of First X-Ray Structure of Rna Containing Guanosine Phosphorodithioate, PDB code: 4rby was solved by P.S.Pallan, M.Egli, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.19
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	40.932, 35.015, 31.873, 90.00, 128.80, 90.00
R / Rfree (%)	18.1 / 21.3

The binding sites of Strontium atom in the First X-Ray Structure of Rna Containing Guanosine Phosphorodithioate (pdb code 4rby). This binding sites where shown within 5.0 Angstroms radius around Strontium atom.
In total 2 binding sites of Strontium where determined in the First X-Ray Structure of Rna Containing Guanosine Phosphorodithioate, PDB code: 4rby:
Jump to Strontium binding site number: 1; 2;

Strontium binding site 1 out of 2 in the First X-Ray Structure of Rna Containing Guanosine Phosphorodithioate


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 1 of First X-Ray Structure of Rna Containing Guanosine Phosphorodithioate within 5.0Å range: probe atom residue distance (Å) B Occ A:Sr401 b:6.1 occ:0.25 SR A:SR402 1.0 9.9 0.2 O A:HOH515 2.7 15.3 1.0 O A:HOH516 2.7 17.8 1.0 O A:HOH585 3.2 64.2 1.0 O4 A:U108 3.4 11.8 1.0 O A:HOH563 3.4 29.9 1.0 O A:HOH580 3.5 34.3 1.0 O A:HOH504 3.6 14.0 1.0 O4 A:U107 4.4 8.1 1.0 O A:HOH505 4.4 16.9 1.0 C4 A:U108 4.4 11.0 1.0 O A:HOH549 4.5 13.2 1.0 C5 A:U107 4.7 8.2 1.0 C5 A:U108 4.9 12.3 1.0 C4 A:U107 4.9 7.5 1.0 O A:HOH506 5.0 16.3 1.0

Strontium binding site 2 out of 2 in the First X-Ray Structure of Rna Containing Guanosine Phosphorodithioate


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 2 of First X-Ray Structure of Rna Containing Guanosine Phosphorodithioate within 5.0Å range: probe atom residue distance (Å) B Occ A:Sr402 b:9.9 occ:0.25 SR A:SR401 1.0 6.1 0.2 O A:HOH585 2.5 64.2 1.0 O A:HOH515 2.7 15.3 1.0 O A:HOH580 2.8 34.3 1.0 O A:HOH504 3.1 14.0 1.0 O A:HOH516 3.2 17.8 1.0 O A:HOH563 4.3 29.9 1.0 O4 A:U108 4.3 11.8 1.0 O A:HOH549 4.3 13.2 1.0 O A:HOH529 4.5 18.1 1.0 O A:HOH505 4.7 16.9 1.0 O4 A:U107 4.8 8.1 1.0 OP2 A:A106 4.9 11.9 1.0 O A:HOH562 4.9 24.5 1.0 C5 A:U107 4.9 8.2 1.0

P.S.Pallan, X.Yang, M.Sierant, N.D.Abeydeera, T.Hassell, C.Martinez, M.Janicka, B.Nawrot, M.Egli. Crystal Structure, Stability and Sirna Activity of Phosphorodithioate-Modified Rnas To Be Published.