Strontium in PDB 8cv9: Structure of Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine

All present enzymatic activity of Structure of Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine:
1.14.11.11;

The structure of Structure of Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine, PDB code: 8cv9 was solved by E.W.Wenger, A.K.Boal, J.M.Bollinger, C.Krebs, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.09 / 1.79
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	44.97, 79.656, 56.017, 90, 111.3, 90
R / Rfree (%)	17.4 / 19.2

The structure of Structure of Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine also contains other interesting chemical elements:

Vanadium

(V)

1 atom

The binding sites of Strontium atom in the Structure of Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine (pdb code 8cv9). This binding sites where shown within 5.0 Angstroms radius around Strontium atom.
In total 2 binding sites of Strontium where determined in the Structure of Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine, PDB code: 8cv9:
Jump to Strontium binding site number: 1; 2;

Strontium binding site 1 out of 2 in the Structure of Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 1 of Structure of Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine within 5.0Å range: probe atom residue distance (Å) B Occ A:Sr413 b:29.4 occ:0.68 O A:HOH729 2.4 33.0 1.0 O A:ASN145 2.5 17.8 1.0 O A:HOH720 2.5 36.0 1.0 O A:HOH553 2.6 39.2 1.0 O A:HOH682 2.7 30.1 1.0 O A:HOH714 2.7 29.3 1.0 C A:ASN145 3.6 18.4 1.0 CA A:SER146 4.3 17.0 1.0 N A:SER146 4.4 17.6 1.0 NH2 A:ARG155 4.4 15.0 1.0 OE2 A:GLU149 4.4 22.5 1.0 O A:HOH779 4.4 38.1 1.0 CA A:ASN145 4.7 19.1 1.0 CB A:ASN145 4.8 20.7 1.0 O A:HOH518 4.8 31.4 1.0 O A:HOH568 4.9 25.4 1.0

Strontium binding site 2 out of 2 in the Structure of Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 2 of Structure of Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine within 5.0Å range: probe atom residue distance (Å) B Occ A:Sr414 b:10.8 occ:1.00 O A:GLY98 2.5 14.2 1.0 OE1 A:GLN95 2.6 14.5 1.0 O A:HOH726 2.6 16.9 1.0 OE2 A:GLU92 2.6 13.5 1.0 OE1 A:GLU92 2.8 13.2 1.0 CD A:GLU92 3.1 13.7 1.0 C A:GLY98 3.6 13.9 1.0 CD A:GLN95 3.6 14.7 1.0 NE2 A:GLN95 4.1 15.7 1.0 CA A:GLY98 4.4 14.0 1.0 N A:GLU99 4.5 14.0 1.0 CA A:GLU99 4.6 14.3 1.0 O A:HOH595 4.6 33.4 1.0 CG A:GLU92 4.6 13.5 1.0 CG A:GLN95 4.8 14.2 1.0 O A:HOH680 4.9 25.8 1.0 CB A:GLN95 4.9 13.7 1.0 O A:HOH616 5.0 10.1 1.0

E.S.Wenger, A.K.Boal, J.M.Bollinger, C.Krebs. Structure of the H6H Hydroxylation Reactant Complex To Be Published.