Strontium in PDB 8cvf: Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine

All present enzymatic activity of Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine:
1.14.11.11;

The structure of Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine, PDB code: 8cvf was solved by E.W.Wenger, A.K.Boal, J.M.Bollinger, C.Krebs, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.56 / 1.53
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	44.783, 79.901, 55.675, 90, 111.24, 90
R / Rfree (%)	18.1 / 20.1

The structure of Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine also contains other interesting chemical elements:

Vanadium

(V)

1 atom

The binding sites of Strontium atom in the Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine (pdb code 8cvf). This binding sites where shown within 5.0 Angstroms radius around Strontium atom.
In total 2 binding sites of Strontium where determined in the Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine, PDB code: 8cvf:
Jump to Strontium binding site number: 1; 2;

Strontium binding site 1 out of 2 in the Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 1 of Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine within 5.0Å range: probe atom residue distance (Å) B Occ A:Sr412 b:9.4 occ:0.95 O A:GLY67 2.5 10.2 1.0 O A:HOH718 2.6 21.7 1.0 O A:HOH545 2.6 17.1 1.0 C A:GLY67 3.6 9.3 1.0 CA A:GLY67 4.2 9.1 1.0 OE1 A:GLU164 4.7 13.5 1.0 N A:LEU68 4.8 9.5 1.0 CD A:PRO69 4.8 9.9 1.0 O A:HOH827 4.8 26.4 1.0 CG A:PRO69 4.9 10.0 1.0 OE2 A:GLU164 5.0 16.0 1.0

Strontium binding site 2 out of 2 in the Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine


Mono view


Stereo pair view

A full contact list of Strontium with other atoms in the Sr binding site number 2 of Structure of L289F Hyoscyamine 6-Beta Hydroxylase in Complex with Vanadyl, Succinate, and Hyoscyamine within 5.0Å range: probe atom residue distance (Å) B Occ A:Sr413 b:22.0 occ:0.74 O A:HOH763 2.4 33.1 1.0 O A:HOH811 2.4 32.5 1.0 O A:ASN145 2.5 15.8 1.0 O A:HOH529 2.6 31.3 1.0 O A:HOH751 2.6 30.7 1.0 O A:HOH738 2.6 23.8 1.0 O A:HOH632 2.8 26.4 1.0 C A:ASN145 3.6 15.8 1.0 CA A:SER146 4.3 14.1 1.0 N A:SER146 4.4 14.9 1.0 NH2 A:ARG155 4.4 13.3 1.0 OE2 A:GLU149 4.4 21.6 1.0 O A:HOH754 4.4 35.4 1.0 CA A:ASN145 4.7 16.9 1.0 CB A:ASN145 4.7 18.5 1.0 O A:HOH519 4.8 28.4 1.0 O A:HOH807 4.8 30.6 1.0 O A:HOH544 4.9 24.9 1.0

E.S.Wenger, A.K.Boal, J.M.Bollinger, C.Krebs. Structure of the L289F H6H Ferryl-Mimicking Complex To Be Published.